Senior Scientist, Analytical Research and Development Nuclear Magnetic Resonance Structure Elucidation Merck Merck 4,122 reviews

Job Description

Our Research Scientists are our Inventors. We identify and target steps in disease mechanisms or pathways that could be inhibited or enhanced. Our goal is to isolate a compound that is effective against a disease target. Using innovative thinking, state-of-the-art facilities and robust scientific methodology, we collaborate to discover the next medical breakthrough.

The Analytical Research and Development Nuclear Magnetic Resonance (NMR) Structure Elucidation team in Rahway, NJ is seeking a motivated Senior Scientist with technical expertise in NMR-based characterization of small molecules, peptides, and large biomolecules to support Merck's modality agnostic discovery and development pipeline. In addition to fundamental NMR skills, we are seeking strong leadership, communication, and collaborative behaviors which support a diverse, inclusive, and productive culture across the team.

Work performed in the NMR group includes, but is not limited to, structure elucidation and characterization, stereochemistry determination, mechanism elucidation, quantitative NMR analysis, identification of process impurities, drug substance and drug product degradants, metabolites and other unknowns. You will provide support for discovery research, process development, and analytical development. The chosen candidate will interact with a diverse array of world-class scientists in a professional work environment and will be focused on making impactful contributions to pipeline projects through NMR problem solving.

We are looking for a highly skilled and motivated individual, who, while capable of working independently, understands and values cross-functional teamwork and will support our common mission in the invention and development of analytical methods for new therapeutic solutions to unmet medical needs. You will collaborate with our team and with synthetic, purification, computational and analytical chemists across the organization in solving challenging structural problems.


Education Minimum Requirements:

  • Ph.D. (or expected by 2021) in chemistry, biochemistry, biophysics, or equivalent with an emphasis in NMR techniques.


Required Experience and Skills:

  • 1+ years' experience in NMR spectroscopy.


Preferred Experience and Skills:

  • 3+ years of experience in structure elucidation with a proven track record of accomplishments in the area of small organic molecule structure elucidation (e.g., natural products, saccharides, pharmaceuticals, etc.)

  • Strong knowledge of organic chemistry, biochemistry or physical chemistry; experience in a medicinal or process chemistry environment is desirable.

  • Comprehensive knowledge of NMR instrumentation, methodology and software.

  • Application of molecular modeling for NMR structure elucidation.

  • Skilled in the use and maintenance of Bruker, Varian or JEOL NMR software and hardware including cryoprobes and the application of NMR automation tools.

  • Technically inclined with the ability to troubleshoot complex instrument problems (e.g., automation, robotic systems, etc.)

  • Evidence of creative application of NMR techniques to problems of pharmaceutical interest.

  • IT literate with the ability to manipulate data workflows in a networked environment (Windows and Linux OS, macros, scrips, etc.). Experience in scientific programming (Perl, Python) is desirable.

  • Experience in other analytical techniques (MS, chromatography, etc.) is desirable.

  • Excellent track record of publications, posters, and speaking engagements.

  • Excellent oral and written communication skills.

  • Excellent interpersonal, collaboration, and teamworking skills.

We are a research-driven biopharmaceutical company. Our mission is built on the simple premise that if we “follow the science” that great medicines can make a significant impact to our world. We believe that a research-driven enterprise dedicated to world-class science can succeed by inventing medicine and vaccine innovations that make a difference for patients across the globe.

ARandD


Who we are …

We are known as Merck & Co., Inc., Kenilworth, New Jersey, USA in the United States and Canada and MSD everywhere else. For more than a century, we have been inventing for life, bringing forward medicines and vaccines for many of the world's most challenging diseases. Today, our company continues to be at the forefront of research to deliver innovative health solutions and advance the prevention and treatment of diseases that threaten people and animals around the world.


What we look for …

In a world of rapid innovation, we seek brave Inventors who want to make an Impact in all aspects of our business, enabling breakthroughs that will affect generations to come. We encourage you to bring your disruptive thinking, collaborative spirit and diverse perspective to our organization. Together we will continue Inventing For Life, Impacting Lives while Inspiring Your Career Growth.


INVENT.


IMPACT.


INSPIRE.


NOTICE FOR INTERNAL APPLICANTS

In accordance with Managers' Policy – Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

If you have been offered a separation benefits package but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.


US and Puerto Rico Residents Only:

If you need an accommodation for the application process please email us at [email protected]

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